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- W2368762433 abstract "Objective To investigate the effect of ulinastatin(UTI) on human blood coagulation and fibrinolysis system in total joint arthroplasty.Methods Sixty ASAⅠ～Ⅱorthopedics patients were randomly divided into UTI group(n=30) in which patients were given UTI 5 000 U/kg and control group(n=30) in which patients were given NS 100 ml.PT,TT,APTT,IB,INR and PAGM were measured at pre-infusion(T0),1 hour after UTI infusion(T1) and 2 hours after UTI infusion(T2).Results APTT and PT at T1(P0.05),and TT at T2(P0.05) were prolonged significantly than the baseline at T0.Compared with control group,APTT and PT at T1(P0.01),and PT and TT at T2(P0.05) were prolonged significantly.There was no difference in PAGM between two groups.Conclusion UTI 5 000 U/kg can improve hypercoagulative status of patients during total joint arthroplasty,which may prevent deep vein thrombosis after surgery." @default.
- W2368762433 created "2016-06-24" @default.
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- W2368762433 date "2012-01-01" @default.
- W2368762433 modified "2023-09-25" @default.
- W2368762433 title "The effect of ulinastatin on human blood coagulation and fibrinolysis system in total joint arthroplasty" @default.
- W2368762433 hasPublicationYear "2012" @default.
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