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- W2368791356 abstract "Objective:To investigate the immune response of porcine transplanted with allogeneic tissue-engineered tooth germ and the influence of CD4/8 with inductive immunosuppressive drugs FK506.Methods Porcine tooth germ cells and ceramic bovine bone were used to construct tissue-engineered teeth and the mixture was implanted into mesenteries.Immunosuppressant FK506 was administrated after implantation.At special time points, the implants were retrieved for histological analysis.Results:There were obvious lymphocyte in-filtrations in the graft after implantation of mesenteries.The levels of CD4+T cells were significantly decreased and the further growth of allogeneic tissue engineered tooth germ in vivo was obvious after administration of FK506.Conclusions:Immunosuppressant FK506 can affect the immune response caused by the implantation of allogeneic tissue-engineered tooth germ.These studies provided a promising experimental foundation for the clinical application of tissue engineered tooth germ in future." @default.
- W2368791356 created "2016-06-24" @default.
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- W2368791356 date "2009-01-01" @default.
- W2368791356 modified "2023-09-24" @default.
- W2368791356 title "Study on Immune Response in Transplantation with Allogeneic Tissue-engineered Tooth Germ" @default.
- W2368791356 hasPublicationYear "2009" @default.
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