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- W2368795931 abstract "Aim To evaluate the signficance and role between ras,c-erbB-2 onc-gene and P 53 tumor suppressor gene expression infected with bacterial L-forms in tumor of C 57 mice.Methods 10 cases of tumor and 13 cases precancerous lesion in mice infected with bacterialL-forms were studied for ras,c-erbB-2,and P 53 expression of protein and mRNA with immunohistochemistry and hybridization in situ.Results The positive rate of P 21 (ras),c-erbB-2 and P 53 protein expression were 60%(6/10),70%(7/10) and 60%(6/10) in 10 cases of tumor mice,and were 15.38%(2/13),15.38%(2/13) and 38.46%(5/13) in 13 cases of precancerous lesion mice.The positive rate of ras,c-erbB-2 and P 53 mRNA expression were 50%(5/10),70%(7/10) and 50%(5/10) in 10 cases of tumor mice,and were 15.38%(2/13),0%(0/13) and 38.46%(5/13) in 13 cases of precancerous lesion mice respectively.Conclusion The results demonstrate that the abnormalities of ras,cerbB-2 and P 53 protein and mRNA expression,infection bacterial L-forms may be one of causes of tumor.They may be related to the pathogenesis and development of tumor of mice." @default.
- W2368795931 created "2016-06-24" @default.
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- W2368795931 date "2001-01-01" @default.
- W2368795931 modified "2023-09-28" @default.
- W2368795931 title "THE SIGNIFICANCE AND ROLE OF RAS,C-ERBB-2,P~(53) GENE EXPRESSION AND INFECTED WITH BACTERIAL L-FORMS IN TUMOR OF C_(57) MICE" @default.
- W2368795931 hasPublicationYear "2001" @default.
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