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- W2368802829 abstract "Aim: To investigate the expression of human kallikrein 15(KLK15) in the primary epithelial ovarian carcinoma and the clinical significance.Methods:Expression of KLK15 proteins in 60 cases of malignant ovarian epithelial tumors 20 cases of benign adenoma and 10 cases of normal orarian tissue were evaluated by immunohistochemical staining.Results: Expression of KLK15 protein in malignant primary ovarian epithelial tumors tissue was 75%(45/60),significantly higher than 40%(8/20) in ovarian benign adenoma and 10%(1/10) in normal tissues(P0.05).There was no statistical significance in the expression rate between benign tissue and normal ovarian tissue(P0.05).Expression of KLK15 protein was higher in the poorly differentiated tumor tissue and in the advanced patients(P0.01),and also in the tumor tissues from the patients with local lymphnode metastases(P0.01).The KLK15 expression was positirely correlated with overall survival of patients(χ2=5.96,P=0.014 6).Conclusion: The overexpression of KLK15 may serve as a useful marker for assessment of the biological behavior of epithelial ovarian cancer and for assessing the malignancy prognosis." @default.
- W2368802829 created "2016-06-24" @default.
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- W2368802829 date "2008-01-01" @default.
- W2368802829 modified "2023-09-28" @default.
- W2368802829 title "Expression of human kallikrein 15 in the epithelial ovarian carcinoma tissue" @default.
- W2368802829 hasPublicationYear "2008" @default.
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