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- W2368836632 abstract "Objective To study the effects of somatostatin and emodin on sphincter of Oddi (SO) in acute necrotizing pancreatitis (ANP). Methods Fifteen dogs were used and the ANP models were induced by retrograde ductal injection of mixture of 5% taurocholic acid and autologous bile.The dogs were then allocated into 3 groups:ANP untreated group,somatostatin group and emodin group.SO manometry including basal pressure (BP) and phasic contractive amplitude (PAC) were investigated before and 5,10,30,60,120,180 minutes after ANP and the administration of above drugs. Results The BP was obviously increased after ANP and Somatostatin can significantly decrease the BP or PCA on SO in ANP,however,Emodin had no any effect on SO. Conclusion The dysmotility of SO plays an important role in the progression of ANP and it may also affect the severity of this disease;somatostatin has beneficial effects on SO in ANP.Although Emodin has effects on ANP,there was no effect on SO in ANP." @default.
- W2368836632 created "2016-06-24" @default.
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- W2368836632 date "1999-01-01" @default.
- W2368836632 modified "2023-09-25" @default.
- W2368836632 title "Effects of somatostatin and emodin on sphincter of Oddi in acute necrotizing pancreatitis in dogs" @default.
- W2368836632 hasPublicationYear "1999" @default.
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