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- W2368850829 abstract "Objective To investigate the performance of Hb A in the prediction of prenatal diagnosising of foetal β-thalassemia and the application of hemoglobin electrophoresis in the second and third trimester of gestation in detecting for maternal blood pollution.Methods In 54 cases there were prior screening for β-globin defects by High risk pregnancies ofβ-thalassemia.The core blood samples which were collecting in the second and third trimester of gestation(between 24 ~28 w) were performed for the prenatal diagnosis with Hemoglobin electrophoresis and genetic testing.Results The Hb A in12 normal cases and 31 mild β-thalassemia cases were observed in(6.3% ± 1.9%) and 2.6% ~ 3.7%,respectively.10 cases of β0-thalassemia included Hb A were 0(n = 6),Hb A were 0.4% ~ 0.7%(n = 4).Besides,one case were suspected as maternal cell contamination.Conclusion The Hb A of hemoglobin electrophoresis was an effective marker to predict the β0-thalassemia,mild β-thalassemia and β-thalassemia intermedia for fetuses.This study has also confirmed that hemoglobin electrophoresis was definitely helpful in detecting for maternal cell contamination." @default.
- W2368850829 created "2016-06-24" @default.
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- W2368850829 date "2014-01-01" @default.
- W2368850829 modified "2023-09-27" @default.
- W2368850829 title "THE HB A OF HEMOGLOBIN ELECTROPHORESIS IN PRENATAL CORD BLOOD PREDICTING FOR β-THALASSEMIA AND MATERNAL CELL CONTAMINATION" @default.
- W2368850829 hasPublicationYear "2014" @default.
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