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- W2368851497 abstract "Objective To investigate the association between complement regulatory proteins CD55, CD59 and ankle-brachial index (ABI) in senile hyperlipidemia. Methods Two hundred and forty-three elderly patients with hyperlipidemia were enrolled in this study and 60 healthy volunteers served as controls. The expressions of CD55, CD59 on leucocytes, and ABI were examined, and the relationship between them was analyzed. Results Compared with healthy controls, the mean fluorescence intensity(MFI) and the percentage of CD55-positive lymphocytes in the elderly patients with hyperlipidemia were significantly decreased(P0.05), MFI of CD55-positive lymphocytes was significantly correlated with waist-hip ratio, waistline, body mass index(P0.05). ABI was more significantly decreased(P0.05) in elderly patients with hyperlipidemia than that in healthy controls; ABI was negatively correlated with age,hsCRP,total cholesterol,systolic pressure, body mass index(P0.05),while was positively correlated with MFI of CD55-positive lymphocytes(P0.05). Conclusions ABI is decreased in the elderly patients with hyperlipidemia. The decrease of ABI might be related with down-regulation of the expression of complement regulatory protein CD55, but not related with CD59." @default.
- W2368851497 created "2016-06-24" @default.
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- W2368851497 date "2013-01-01" @default.
- W2368851497 modified "2023-09-24" @default.
- W2368851497 title "Study on the relationship between complement regulatory proteins CD55, CD59 and ankle-brachial index in senile hyperlipidemia" @default.
- W2368851497 hasPublicationYear "2013" @default.
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