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- W2368854523 abstract "Aim: To determine the infection rate and pathogenicity of transfusion transmitted virus (TTV) in the children (7～12 years old) with elevated alanine aminotransferase (ALT). Methods: Nested PCR was used to detect serum TTV DNA from 62 children with elevated serum ALT and 75 children with normal serum ALT during their routine medical checking up. PCR reamplification products were separated by electrophoresis. Serum marks of hepatitis virus A, B and C were simultaneously determined using routine ELISA methods. Results: In the children with elevated ALT, TTV DNA positivity was detected in 129% (8/62), and there were 3 and 1 cases with combined positive HBsAg (48%) and one case with anti-HCV (16%), respectively. In the children with normal ALT, TTV DNA positivity was only detected in 2.7% (2/75). There was a significant difference between them (P0.05). Conclusion: TTV infection exists in the children, and can cause live function damage besides HBV, HCV and HAV infection. There is an overlapping TTV and hepatitis virus infection in the children with abnormal ALT." @default.
- W2368854523 created "2016-06-24" @default.
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- W2368854523 date "2003-01-01" @default.
- W2368854523 modified "2023-09-26" @default.
- W2368854523 title "The transfusion transmitted virus infection in the children with elevated level of alanine aminotransferase" @default.
- W2368854523 hasPublicationYear "2003" @default.
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