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- W2368898049 abstract "Objective To investigate the effect of isoflurane at different concentration on the quantitative electroencephalogram(SEF and BIS) , intracranial pressure(ICP) and hemodynamics during neurosurgery Methods Thirty ASA grade Ⅰ Ⅱ patients with saddle tumor ,scheduled for selective operation, were randomly divided into three groups after induction with fentanyl propofol vecuronium and intubation Anesthesia was maintained with inhalation of 0 5,1 0 or 1 5 MAC of isoflurane in each group respectively MAP,HR,ICP,SEF and BIS were recorded before induction,reaching the designed MAC, at incision ,sawing bones and opening dura Results SEF and BIS decreased significantly with increases in concentration of isoflurane MAP decreased markedly at1 5 MAC compared with that at 0 5 MAC (P0 01) MAP,SEF and BIS increased during neurosurgery at 0 5 MAC,while remained unchanged at 1 0MAC and 1 5MAC The rash of EEG depression was found at 1 5MAC ICP was kept stable in each group during whole procedures Conclusions Inhalation of 1 0MAC of isoflurane is indicated for anesthesia maintenance during neurosurgery" @default.
- W2368898049 created "2016-06-24" @default.
- W2368898049 creator A5045025757 @default.
- W2368898049 date "2000-01-01" @default.
- W2368898049 modified "2023-09-28" @default.
- W2368898049 title "Effects of isoflurane inhalation on the electroencephalogram ,intracranial pressure and hemodynamics during neurosurgery" @default.
- W2368898049 hasPublicationYear "2000" @default.
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