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- W2368917182 abstract "Objective To investigate the effects of sesquiterpenoids on the proliferation of prostate cancer cells.Methods The growth of prostate cancer cells treated with sesquiterpenoids from myrrh was determined by MTT.The cell cycle was analyzed by flow cytometry.Also the expressions of p21WAF/CIP1(p21)and cyclinD at mRNA levels were determined by reverse transcription PCR(RT-PCR).Results The two sesquiterpenoids significantly inhibited the proliferation of prostate cancer cells and caused a G0/G1 arrest,also they induced the expression of p21 and decreased the expression of cyclinD.Conclusion Over-expression of p21 and decrease of cyclinD might contribute to the two sesquiterpenoid-mediated inhibitory effects on prostate cancer cell growth." @default.
- W2368917182 created "2016-06-24" @default.
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- W2368917182 date "2007-01-01" @default.
- W2368917182 modified "2023-09-24" @default.
- W2368917182 title "Effect of sesquiterpenoids on proliferation activity of prostate cancer cells" @default.
- W2368917182 hasPublicationYear "2007" @default.
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