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- W2368983607 abstract "Objective To assess the clinical value of urine NAG activity and blood CysC in detecting early renal injuries after extracoporeal circulation.Methods Forty infant undergoing cardiac surgery by cardiopulmonry bypass with normal preoperative renal function were included in CPB group;while 16 patients accepted thoracic surgery without CPB were included in control group.Blood Cr,CysC and urine NAG were examined in CPB group and in control group during preoperation,3 hours after operation and 24 hours after operation.NAG activities and Cr clearence were caculated at the same time.Linear correlation and regression were used to determine the relationships between urine NAG/Cr vs serum Cr as well as blood CysC vs Cr clearence.Results(1)Urine NAG/Cr vs serum Cr as well as blood CysC vs Cr clearence were of positive correlations,urine NAG/Cr and blood Cysc remained high level 24 hours after operation,but at the same time serum Cr and Cr clearence have already dropped to normal.(2)Urine NAG/Cr values were significantly higher in CPB group than that in control group during 3 hours and 24 hours postoperatively.(3)Cr clearence and blood CysC showed no difference both in and between the two groups perioperatively.Conclusion Urine NAG/Cr and blood CysC could be used as sensitive and specific indications for monitoring early changes on renal function in patients accepted extracorporeal circulation;CPB may cause renal tubule injury." @default.
- W2368983607 created "2016-06-24" @default.
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- W2368983607 date "2008-01-01" @default.
- W2368983607 modified "2023-09-23" @default.
- W2368983607 title "Variation of Urine NAG Activity and Blood CysC after Padiatric Heart Surgery and Its Clinical Significance" @default.
- W2368983607 hasPublicationYear "2008" @default.
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