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- W2368989866 abstract "Objective To study the influence of losartan on level of serum(UA) in patients with congestive heart failure(CHF).Methods The concentrations of serum UA in 80 CHF patients according class of cardiac function were compared.The 80 CHF patients were randomly averagely divided into losartan and enalapril groups.The treatment time of the two groups was 12 weeks.The level of serum UA was examined before and after treatment respectively.Results The concentrations of serum UA in NYHA cardiac function class Ⅰ~Ⅱ、Ⅲ、Ⅳ was(344±105)μmol/L、(417±112)μmol/L、(488±123)μmol/L.respectively and The level of serum UA in Ⅳ was much higher than those in class Ⅰto class Ⅱ(P0.01),The level of serum UA in losartan group before and after treatment was(414±112)μmol/L、(273±99)μmol/L(P0.05).while the UA level of enalapril group was no significant change(P0.05).Conclusion The concentration of serum UA in CHF patients is obviously raise along with the CHF worsened.Losartan can improve cardiac function and has a role of decreasing the serum uric acid." @default.
- W2368989866 created "2016-06-24" @default.
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- W2368989866 date "2008-01-01" @default.
- W2368989866 modified "2023-09-25" @default.
- W2368989866 title "Influence of losartan on level of serum uric acid in patients with congestive heart failure" @default.
- W2368989866 hasPublicationYear "2008" @default.
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