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- W2368992032 abstract "Objective: To explore the clinical features,diagnosis and therapy of acute fatty liver of pregnancy(AFLP) to reduce the mortalities of pregnant women and perinatal infants.Methods: The clinical manifestations,laboratory examination,diagnosis,treatment,maternal and infantile outcomes of 26 patients who went to the hospital because of AFLP were analyzed retrospectively.Results: Among 26 patients,21 patients were found with anorexia,fatigue and nausea at early stage,19 patients were found with skin jaundice,26 patients were found with increase of liver enzymes and abnormal coagulation function,21 patients were found with increase of bilirubin,19 patients were found with acute renal insufficiency,16 patients were found with disseminated intravascular coagulation(DIC),18 patients were found with postpartum hemorrhage,6 patients were found with hepatic encephalopathy,5 patients were found with uterine inertia;Blynch suture was conducted as early as possible during operation,hysterectomy didn't be performed;one parturient woman died and three fetal deaths were found;four neonates were found with mild asphyxia and one neonate was found with severe asphyxia,all the neonates were rescued successfully.Conclusion: Prenatal examination should be strengthened,digestive tract symptoms and abnormal laboratory examination results during the third trimester of pregnancy should be paid more attention to,the patients with AFLP should be diagnosed as early as possible,and pregnancy should be terminated quickly,multi-disciplined and comprehensive treatment can effectively reduce maternal and infantile mortalities." @default.
- W2368992032 created "2016-06-24" @default.
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- W2368992032 date "2013-01-01" @default.
- W2368992032 modified "2023-09-25" @default.
- W2368992032 title "Clinical analysis on 26 patients with acute fatty liver of pregnancy" @default.
- W2368992032 hasPublicationYear "2013" @default.
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