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- W2368996504 abstract "Objective To investigate the expression of α-basic-crystallin( αB-crystallin) in basal-like breast cancer( BLBC),and analyze the association between its expression and the clinicopathological characteristics in BLBC. Methods The SP immunohistochemical technique was used to examine the expression of αB-crystallin in 108 cases of BLBC and 342 cases of non-basal-like breast cancer( NBLBC). Results By statistical analysis,it showed that the positive rate of αB-crystallin was 56. 5% in BLBC,significantly higher than 7. 9% in NBLBC( P 0. 05). The expression of αB-crystallin was found to be positively correlated with histological grading of tumor( r =0. 313,P 0. 001),but not with age,tumor size and lymph node metastasis( P 0. 05). Conclusion αB-crystallin may play an important role in the progression of BLBC. Furthermore,it also may be a marker which can predict poor clinical outcome in BLBC." @default.
- W2368996504 created "2016-06-24" @default.
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- W2368996504 date "2013-01-01" @default.
- W2368996504 modified "2023-09-23" @default.
- W2368996504 title "Clinical significance and expression of αB-crystallin in basal-like breast cancer" @default.
- W2368996504 hasPublicationYear "2013" @default.
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