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- W2369004122 abstract "Objective To study the effects of salt restriction on blood pressure in hypertensive patients with chronic kidney disease(CKD).Methods From July to December,2006,26 hypertensive CKD patients with 24 h urinary sodium excretion(UNa)over 100 mmol/d were enrolled and received dietary education and sodium spoon.Their BP level,blood/urine electrolytes,serum creatinine and amount of urinary protein were measured before-and after-8 weeks.Anti-hypertension therapy kept unchanged during the observation period and those with UNa decreased less than 10% at the end of observation were considered as salt restriction failure.Results Eighteen patients succeeded with a reduction of UNa from(243.8±71.2)mmol/d to(135.0±49.1)mmol/d(P0.01).Their average BP level reduced 11.4 mm Hg systolicly(P0.01)and 6.8 mm Hg diastolicly(P=0.008),respectively.The mean blood pressure(MBP)reduced averagedly 8.4 mm Hg(P=0.001),accompanied with some decrease of urinary protein amount.Eight patients failed to restrict their salt intake with 24 h UNa(166.4±41.4)mmol/d vs(203.3±67.3)mmol/d(P=0.069).No significant changes could be observed in their systolic BP,diastolic BP,MBP and amount of urinary protein.Conclusion Restriction of dietary salt intake itself can bring beneficial effect to BP control and urinary protein control in hypertensive CKD patients." @default.
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- W2369004122 date "2008-01-01" @default.
- W2369004122 modified "2023-09-23" @default.
- W2369004122 title "Effect of dietary salt restriction on blood pressure of hypertensive patients with chronic kidney disease" @default.
- W2369004122 hasPublicationYear "2008" @default.
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