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- W2369011839 abstract "Objective To investigate the dynamic changes and its clinical significance of serum neuron-specific enolase(sNSE)in the patients with cerebral infarction.Methods The trial group was 75 patients with cerebral infarction,and the control group was 30 healthy people.The venous blood was collected at different times after cerebral infarction to get the serum samples and measure the sNSE by means of ELISA method.Results ①The sNSE concentration of the trial group was significantly higher than that of the control group,which were(7 25±2 14)ng/mL and (3 97±1 12)ng/mL respectively, P 0 01;②There was a positive relationship between the sNSE concentration and the volume of the infarction.The bigger the infarction volume was,the higher the sNSE concentration was;③There were dynamic changes of the sNSE.Obvious changes of the sNSE concentration were not found within 4 hours after the infarction.They began to increase gradually after 6 hours and get the highest level in 2 days, persist for 5～7 days,which decreased to the normal level after 14 days;④There was a positive relationship between the blood sugar level and the sNSE concentration,the higher the blood sugar level was,the higher the sNSE concentration was.⑤The sNSE level was associated with the prognosis of the patients with cerebral infarction.Conclusion The sNSE concentration which had a dynamic change after cerebral infarction,and was associated with the infarction volume and the prognosis of the patients,and it changed early compared with CT or MRI scaning.We could decide the treatment according to the sNSE concentration." @default.
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- W2369011839 date "2003-01-01" @default.
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- W2369011839 title "Dynamic change and its clinical significance of serum neuron-specific enolase in patients with cerebral infarction" @default.
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