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- W2369040804 abstract "Metabonomes reflects the systematic status of the organism accurately,sensitively and impersonally. To evaluate the therapeutic effects by means of metabonomics will overcome the deficiency of uncertainty with the traditional diagnostic methods including inspection,auscultation and olfaction,inquiry,and palpation. The impact of the variation of prescriptions dosage on efficiency will be shown clearly through the change tendencies of metabonome spectra. Consequently,a new insight is obtained for the dose-effect relationship and its material basis. The ambiguous dose-effect relationship of tranditional Chinese medicine (TCM) prescriptions has long been controversial. It is one of the most important reasons that the therapeutic effect of this kind of medicines cannot be evaluated quantitatively. Based on the review of the application of metabonomics in modern study of TCM,we suggest to carry out the study on dose-effect relationship of prescriptions,in which the techniques of metabonomics are employed to comprehensively evaluate the therapeutic effect of prescriptions,and the variation of metabonomes in the course of disease devecopment and treatment is traced." @default.
- W2369040804 created "2016-06-24" @default.
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- W2369040804 date "2009-01-01" @default.
- W2369040804 modified "2023-09-26" @default.
- W2369040804 title "Research advances of metabonomics and application in the study of dose-effect relationship of prescriptions" @default.
- W2369040804 hasPublicationYear "2009" @default.
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