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- W2369073959 abstract "Objective: To make research on the internal mechanism of treating experimental chronic bronchitis with Kechuanning capsules. Method: We duplicated the animal model of chronic bronchitis with refined smoking fumigated method, the rats were allocated to model group, high dose group, low dose group, Guilong group and nomal control group that didn't treated. Made intervention with high and low dose Kechuanning as well as Guilong Kechuanning(another medicine of the similar kind)and determined the ET 1 NO contents in the blood serum, lung tissue and BALF of each group. Result: The ET 1 contents in the blood serum, lung tissue and BALF of the model group were significantly improved than that of the nomal group( P 0 01), while the NO contents were significantly reduced than the nomal group (P 0 01). Compared with the model group, the ET 1 contents in the blood serem, lung tissue and BALF of the high dose group and Guilong group and in the blood serum of the low dose group were all significantly reduced( P 0 05 or P 0 01). The NO contents in the blood serum, lung tissue and BALF in each treatment group were significantly increased( P 0 05 or P 0 01). The ET 1 contents in the blood serum and lung tissue of the high dose group were lower than that of the Guilong group( P 0 01), the NO contents in the blood serum, lung tissue and BALF were higher than that of the Guilong group( P 0 05 or P 0 01). Conclusion: Kechuanning capsules could control inflammatory reaction by reducing the contents of ET 1 and increasing the contents of NO." @default.
- W2369073959 created "2016-06-24" @default.
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- W2369073959 date "2002-01-01" @default.
- W2369073959 modified "2023-09-25" @default.
- W2369073959 title "Effect of Kechuanning Capsules on the ET-1 & NO Contents in the Blood serum,Lung Tissue and Bronchial Alveoli Lavage Fluid(BALF) of Rat with Chronic Bronchitis" @default.
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