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- W2369079292 abstract "To research the structure-activity relationship (SAR) of glycinamide-bearing compounds that used as inhibitors of dipeptidyl peptidase IV (DPP-IV), P32/98 and compound A were chosen as the leading compounds, heterocycles containing nitrogen atom were introduced to form amide, and different residues on a-position of carbonyl were designed. The nineteen designed compounds were synthesized by a simple route and were evaluated as inhibitors of DPP-IV. All of the structures were characterized by 1H NMR and HRMS. The preliminary SAR result was obtained." @default.
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- W2369079292 date "2010-11-01" @default.
- W2369079292 modified "2023-09-22" @default.
- W2369079292 title "[Design, synthesis and in vitro activity of glycinamide-bearing compounds as DPP-IV inhibitors]." @default.
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