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- W2369263898 abstract "Objective To evaluate the clinical significance of Thymosin α1 in the treatment of malignant tumor.Methods 15 patients were treated with Thymosin α1(Treatment group)with doses of 1.6mg subcutaneous injection twice weekly,with a median course of 3.5 months.The number of Ag-NORs of peripheral blood T lymphocyte was used as a marker for monitoring immune activity.The number of Ag-NORs was detected in 15 cases of health controls,15 patients in Treatment group and 15 patients with malignant tumor without use of Thymosin α1(Non-treatment group).The dynamic variation of the number of Ag-NORs before and after administration of Thymosin α1 in Treatment group were evaluated.Results The number of Ag-NORs of peripheral blood T lymphocyte in health controls was higher than that in Treatment group and Non-treatment group(P0.01).No significant difference of the number of Ag-NORs between Treatment group and Non-treatment was found(P0.05).The number of Ag-NORs after administration of Thymosin α1 was higher than that before administration (P0.05).Conclusion Patients with malignant tumor show significant immunodeficiency compared with healthy controls and Thymosin α1 may play a role in regulating and enhancing cellular immune activity in patients with malignant tumor." @default.
- W2369263898 created "2016-06-24" @default.
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- W2369263898 date "2002-01-01" @default.
- W2369263898 modified "2023-09-26" @default.
- W2369263898 title "Preliminary application of Thymosin α1 in the treatment of malignant tumor" @default.
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