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- W2369361998 abstract "Objective To observe the change of stathmin and β-tubulinⅢ expression in NSCLC and its influence to taxol sensitivity.Methods Expression of stathmin and β-tubulinⅢ in 32 patients with NSCLC who received radical surgery paclitaxel-based chemotherapy were determined by immunohistochemical method.It is that the correlation of their expression analized with prognosis and prediction value in chemotherapy.Results The positive rates of stathmin,β-tubulinⅢ were 52.8% and 62.6%,significant more than inflammatory pseudotumor(P0.05).The positive rates of stathmin have significant difference in poorly differentiated group and lymphatic metastasis group(P0.05);The positive rates of β-tubulin Ⅲ have significant difference in poorly differentiated group and Ⅲ~Ⅳ state group(P0.05).The expression of stathmin,β-tubulinⅢ in the patients who had postoperative chemotherapy were subdivided into two group(all positive,all negative),there showd significant survival difference between all positive and all negative.Conclusion The expression of stathmin and β-tubulin Ⅲ increase in NSCLC tissues.It suggests that the tumor is malignant taxol-unsensitive and poor prognosis." @default.
- W2369361998 created "2016-06-24" @default.
- W2369361998 creator A5052800192 @default.
- W2369361998 date "2010-01-01" @default.
- W2369361998 modified "2023-09-24" @default.
- W2369361998 title "Change of stathmin andβ-tubulinIII expression in NSCLC and its influence to taxol sensitivity" @default.
- W2369361998 hasPublicationYear "2010" @default.
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