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- W2369373002 abstract "In order to study the effect of Streptococcus suis on immune response of growing pigs,twelve 7-week-old hybrid healthy pigs were randomly allotted to two groups:the control and the test group.Pigs in the test group were developed a typical subacute Streptococcosis suum by inoculating subcutaneously 0.45 billion of pure living Streptococcus suis (type C 55126) per 1.0 kg body weight.Some immunity parameters were tested on days 0,7,14,21 and 28 after inoculation.Leukocytes were counted with microscope and differential leukocyte counts performed on Giemsa-stained blood smears.The effect on the nitroblue tetrazolium(NBT) reduction of neutrophil was used to determin its phagocytic ability.Lymphocyte proliferation was determined by using the mitogens PHA.The total serum IgG concentration was measured by radial single immunodiffusion.A 50% hemolytic test was used to investigate the complement activity in serum.Whereas,a phytohemagglutinin(PHA) skin test was used to investigate in vivo immunity.The results indicated that the mean leukocyte counts on day 7 after inoculation was higher than that in the control group.Inaddition,compared with the control group,the mean percent of neutrophil in the test group was lower,whereas the percent of lymphocytes was higher on day 14,21,28 after inoculation.The nitroblue tetrazolium(NBT) reduction by neutrophil was significantly higher(P0.01) than that in the control group on day 7,14,21,28 after inoculation.In vivo proliferation to phytohemagglutinin(PHA) of lymphocytes was significantly lower than that in the control group on day 7,14,21,28 after inoculation.But delayed-type hypersensitivity(DTH) to PHA was lower(P0.05) only on the 21 st day after inoculation.The IgG level in serum was lower(P0.05) on day 7,but was significantly higher(P0.01) on the 14 th day after inoculation,and reached the standard level on day 21,28.The complement activity in serum was lower(P0.05) than the control group." @default.
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- W2369373002 date "2002-01-01" @default.
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- W2369373002 title "Immune Response of Growing Pigs to Streptococcus suis" @default.
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