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- W2369378276 abstract "Objective:To prepare and analyze the biodistribution of 186 Re lipiodol(RL) in patients with primary liver cancer(PLC), assessing the potential of RL as a radiopharmaceutical agent for the treatment of PLC.Methods:RL was synthesized from 186 Rhenium and lipiodol through physical and chemical procedure.Doses of RL ranged from 1 110 MBq to 2 220 MBq per patient depending on the size of tumors.Quantitative gamma camera imaging(ECT) and gamma counting of serum and urine were used to obtain data for dosimetry estimation.Results:In the hepatic tumor RL was selectively retained and radioactivity remained high throughout this study.The ratio of tumor concentration to the normal liver tissue concentration(T/NT ratio) was (10 14)/1 48 h after injection of RL.The main side effects of this therapy were transient fever and anorexia.No unacceptable toxicity was observed.Conclusion:The biodistribution and imaging results demonstrate that RL selectively localize in tumor, indicating RL may be a potential internal radiopharmaceutical agent for the treatment of primary liver cancer." @default.
- W2369378276 created "2016-06-24" @default.
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- W2369378276 date "2003-01-01" @default.
- W2369378276 modified "2023-09-25" @default.
- W2369378276 title "~(186)Re-lipiodol as a new radiopharmaceutical agent for primary liver cancer:preparation and biodistribution" @default.
- W2369378276 hasPublicationYear "2003" @default.
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