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- W2369389048 abstract "Objective To study the influence of methanol extract of Radix Ampelopsis with different polarity on myeloma cell line SP20.Methods After culturing myeloma cells SP20 in vitro,the cell morphological changes were observed under optical microscope,and influence of methanol extraction parts of Radix Ampelopsis with different polarity on SP20 myeloma cells proliferation was detected by MTT assay.Results After co-cultured with the different polar extraction parts of Radix Ampelopsis for 48 hours,SP20 cells showed apoptotic morphological changes under optical microscope.Chloroform,5-fluorouracil,ethyl ether and ethyl acetate part had inhibition on the proliferation of SP20(P 0.05,P 0.01),and normal butanol part had the lowest inhibition ratio(P 0.05)compared with the solvent blank group.Inhibition ratio of ethyl acetate,ethyl ether and chloroform parts of Radix Ampelopsis was in decreasing sequence on the survival of SP20.Conclusion Radix Ampelopsis methanol extract can significantly inhibit the growth of SP20 myeloma cells and promote the apoptosis of SP20." @default.
- W2369389048 created "2016-06-24" @default.
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- W2369389048 date "2013-01-01" @default.
- W2369389048 modified "2023-09-23" @default.
- W2369389048 title "Influence of Methanol Extract of Radix Ampelopsis on Proliferation of Myeloma Cell Line SP20" @default.
- W2369389048 hasPublicationYear "2013" @default.
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