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- W2369460960 abstract "Objective To investigate COX-2 expression in HCC and its clinical application. Methods The COX-2 expression was examined in 38 matched sets of HCC specimens and adjacent liver, and seven normal liver tissues using immunohistochemistry and reverse transcription-polymerase chain reaction(RT-PCR). Results The COX-2 expression was significantly higher in well differentiated HCC than moderated HCC and poor differentiated HCC (P 0.01 respectively), and adjacent non-tumoral liver tissues(P 0.01). The COX-2 was not expressed in normal liver tissues. There was no significant difference among adjacent nontumors tissues, moderated HCC and poor differentiated HCC (P 0.05, respectively). Conclusions The overexpression of COX-2 may involve in carcinogensis of well differentiated HCC, it may play a role in the early stages of hepatocarcinogensis." @default.
- W2369460960 created "2016-06-24" @default.
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- W2369460960 date "2005-01-01" @default.
- W2369460960 modified "2023-09-28" @default.
- W2369460960 title "Clinical significance of cyclooxygenase-2 expression in hepatocellular carcinoma and adjacent nontumors tissues" @default.
- W2369460960 hasPublicationYear "2005" @default.
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