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- W2369586033 abstract "Objective: To research the different treatments of Bushen Qudu Decoction and Uremic Clearance Granule on the same syndrome of Qi deficiency of spleen and kidney of chronic renal failure( CRF). And to make sure the function and mechanism of Bushen Qudu Decoction. Methods: 68 patients who met the inclusion and excluded criteria were divided into treatment group and control group by a non- randomized controlled method. They were all routinely treated by the same therapeutic method while the treatment group was treated by Bushen Qudu Decoction with the other group treated by Clearance Granule. The treatment was for 3 months. We studied the floating results of the 2 groups' syndrome,serum creatinine( SCr),blood urea nitrogen( BUN),blood uric acid( BUA),serum albumin( ALB),hemoglobin( Hb),transforming growth factor- β1( TGF- β1) and bone morphogenetic protein- 7( BMP- 7). Results: The results of the 2groups' SCr,BUN,BUA,ALB,Hb,TGF- β1,BMP- 7 and CCr were all improved significantly( P 0. 05) and the treatment group held more significant results than the control group in SCr,BUN,BUA,ALB,Hb,TGF- β1,BMP- 7 and CCr( P 0. 01). The post- treatment of the 2 groups showed more significant results in SCr,BUN,ALB and CCr( P 0. 05). And expression of TGF- β1showed a positive correlation with BMP- 7. Conclusions: Bushen Qudu Decoction is used widely and can conform to the treatment according to syndrome differentiation. Its effectiveness is more significant than Uremic Clearance Granule in improving renal function,glomerular filtration function and serum albumin level. It also can reduce the expression of TGF- β1and promote BMP- 7." @default.
- W2369586033 created "2016-06-24" @default.
- W2369586033 creator A5024644172 @default.
- W2369586033 date "2014-01-01" @default.
- W2369586033 modified "2023-09-23" @default.
- W2369586033 title "Comparison Research on Treatment of Bushen Qudu Decoction in Qi Deficiency of Spleen and Kidney Syndrome of Chronic Renal Failure" @default.
- W2369586033 hasPublicationYear "2014" @default.
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