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- W2369696823 abstract "Objective: To observe the ef ect of SangjfiMixture in the treatment of the hypertention patients liver-fire with phlegm syndrome) via the toll like recepter4(TLR4), inl ammatory factors including interleukin 6(IL-6) and tumor necrosis factor-α(TNF-α). Methods: 60 cases of hypertension with liver-fire with phlegm syndrome, were randomly divided into treatment group and control group with 30 cases in each, both received Benazapril and(or) Felodipine treatment, the treatment group received SangjfiMixture as additional treatment. Throughout the 28 days` observation period, the indicators such as blood pressure, symptom scores, peripheral blood mononuclear cells TLR4, IL-6 and TNF-α were measured before and after treatment. Results: After the treatment, the blood pressure, symptom scores, peripheral blood mononuclear cells TLR4, IL-6 and TNF-α of the two groups were both decreased compared with the data before the treatment(P0.05), while the treatment group decreased more significantly than the control group(P0.05). Conclusion: SangjfiMixture can improve the anti-hypertensive eficacy, alleviate the clinical symptoms of patients who are diagnosed as overabundant liver-fire with phlegm syndrome and decrease the expression of Toll Like Recepter4(TLR4), inl ammatory factors IL-6 and TNF-α located on the peripheral blood mononuclear cell surface, consequently suppresses the immunological and inl ammatory reaction." @default.
- W2369696823 created "2016-06-24" @default.
- W2369696823 creator A5088486896 @default.
- W2369696823 date "2014-01-01" @default.
- W2369696823 modified "2023-09-26" @default.
- W2369696823 title "Clinical research of Sangji Mixture on the immunological and inflammatory reaction in hypertension of overabundant liver-fire with phlegm syndrome" @default.
- W2369696823 hasPublicationYear "2014" @default.
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