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- W2369711135 abstract "Objective To observe the effect of cilostazol for stable angina pectoris and on serum adiponectin(APN),endothelin(ET-1)and nitric oxide(NO)effects.Methods Selected 86 cases of stable angina pectoris patients were randomly divided into observation group and control group,43 cases in each group.Two groups of patients in the treatment of primary disease,hyperlipidemia,atherosclerotic plaque,symptomatic treatment than that of control group,the control group was given aspirin tablets,the observation group given cilostazol tablets orally,for 12 weeks.During the treatment of angina attack frequency and changes in blood APN,ET-1 and NO of the two groups of patients were observed.Results During the treatment two groups of patients with angina and nitroglycerin dosage number comparison,there was no significant difference(P0.05).Serum APN,NO levels were higher in the observation group after treatment than that of control group,the serum level of ET-I was obviously lower than that of control group,the difference had statistical significance(P0.05).Conclusion Cilostazol has not only good antithrombotic effect,but also has the elevation of serum APN,plasma NO and ET-1 regulate balance,thus resisting atherosclerosis and protect vascular endothelial function." @default.
- W2369711135 created "2016-06-24" @default.
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- W2369711135 date "2013-01-01" @default.
- W2369711135 modified "2023-09-24" @default.
- W2369711135 title "Effect of Cilostazol on Patients with Stable Angina Pectoris Adiponectin and Endothelin-1 and Nitric Oxide" @default.
- W2369711135 hasPublicationYear "2013" @default.
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