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- W2369726637 abstract "In order to observe the effect of low dose 12C6+ irradiation on cell cycle and DNA damage in mouse thymus and spleen cells the mice were whole-body irradiated with 0,10,50,75,100 and 250mGy 12C6+ ion and executed six hours after.Flow cytometry was used to test the changes on thymus and spleen cell cycle and the frequen-cies of cells with tail moment and the tail lengths were determined by the single cell gel electrophoresis.The results show that the percentages of G0/G1 phase cells reduce and the percentages of S phase cells increase significantly in thymus compared with control(p0.05),while the percentages of G0/G1 phase cells increase and the percentages of S phase cells decrease obviously in spleen of mice(p0.01).Similarly,the length of the tails and the number of cells with tail rise as the absorbed dose increased,which has the obviously dose-effect dependent relationship.Low dose 12C6+ irradiation can effectively stimulate DNA synthesis in thymus and can be inhibited at G0/G1 in spleen of mice.At the same time,it can induce DNA damage along with the absorbed doses." @default.
- W2369726637 created "2016-06-24" @default.
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- W2369726637 date "2008-01-01" @default.
- W2369726637 modified "2023-09-24" @default.
- W2369726637 title "Effect of low dose ~(12)C~(6+) irradiation on cell cycle and DNA damage in mouse thymus and spleen cells" @default.
- W2369726637 hasPublicationYear "2008" @default.
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