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- W2369727742 abstract "Objective To observe the clinical effect of adefovir dipivoxil in the treatment of liver cirrhosis patients with low viral load. Methods Seventy-four liver cirrhosis patients with low viral load were divided into two groups according to the random number table,the control group( 37 cases) was given oral lamivudine( 100 mg / d),while the observation group( 37cases) was given adefovir Dipivoxil( 10 mg / d) besides the administration in the control group. The treatment lasted for 48 weeks in both groups,the patients' biochemical indexes and curative effect were observed after treatment. Results The alanine aminotransferase( ALT),serum albumin( ALB),total bilirubin( TBIL),hyaluronic acid( HA) and other biochemical indexes improved significantly after the 48-week treatment,which improved more significantly in the observation group( P 0.05). The negative rate of hepatitis B virus genes( HBV-DNA),conversion rate of hepatitis B virus e antigen( HBeAg),recovery rate of ATL in the observation group were significantly higher than those in the control group( P 0. 05),while the HBV-YMDD mutation rate was lower than that in the control group( P 0. 05). Conclusion Adefovir dipivoxil has better virological and biochemical responses in the treatment of liver cirrhosis patients with low viral load,with mild adverse reactions,it can be taken safely for a long time." @default.
- W2369727742 created "2016-06-24" @default.
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- W2369727742 date "2014-01-01" @default.
- W2369727742 modified "2023-09-26" @default.
- W2369727742 title "Clinical Study of Adefovir Dipivoxil in Treatment of Liver Cirrhosis Patients with Low Viral Load" @default.
- W2369727742 hasPublicationYear "2014" @default.
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