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- W2369754711 abstract "Objective:TO clarify the types and molecular mechanism of the HPFH discovered by us.Methods:By starch-agar mixed gel electrophoresis,HbF level was determinated by celulose by acid elution method.The deletion of β globin gene and the number of a globin gene was established by many endonucleases.Results:Differing from common HPFH,β globin gene deleted only and a globin gene was in existence in this case.This deletion was as long as 27kb,including all β globin gene and its 3’HSI region.The globin genotype of proband was ααα/αα,his father’s αα/αα.Conclusion:This HPFH is of Southeast Asian type and belong to β°thalassemia.The high level of HbF may be related to proband who has one more globin gene." @default.
- W2369754711 created "2016-06-24" @default.
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- W2369754711 date "2004-01-01" @default.
- W2369754711 modified "2023-09-25" @default.
- W2369754711 title "Southeast Asian HPFH or Southeast Asian β°-Thalassemia" @default.
- W2369754711 hasPublicationYear "2004" @default.
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