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- W2369791808 abstract "Objective To investigate the factors influencing plasma brain natriuretic peptide(BNP) in patients with restrictive cardiomyopathy(RCM).Methods Twenty RCM patients diagnosed by biopsy were enrolled.Clinical features,echocardiograph and right heart catheter data were collected in all patients.The plasma BNP levels were determined.The associations between plasma BNP levels and the collected data were analyzed.Results Plasma BNP level was elevated to(792.3±1045.9) ng/L in RCM patients. There was no association of BNP with age.gender.NYHA class,and medications in RCM patients.Plasma BNP level was correlated significantly(P0.05) with echocardiography parameters.including transmural E/A ratio(r= 0.46).E-wave deceleration time(r = -0.59),isovolumic relaxation time(r = -0.45),mitral annular lateral early diastolic velocity(E') on tissue Doppler imaging(r = -0.45) and E/E' ratio(r = 0.86).BNP levels were correlated significantly(P0.05) with right atrial pressure(r = 0.45).right ventricular diastolic pressure(r = 0.56) and pulmonary capillary wedge pressure(r = 0.46) detected by right heart catheterization(P0.05). Multivariate regression analysis showed that BNP was correlated independently with mitral E/E' ratio(β=0.69,P0.05). Conclusion In RCM patients,plasma BNP levels are elevated and correlated with left ventricular diastolic function indices determined by Doppler echocardiographic signs and diastolic pressure determined by right heart catheterization." @default.
- W2369791808 created "2016-06-24" @default.
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- W2369791808 date "2011-01-01" @default.
- W2369791808 modified "2023-09-23" @default.
- W2369791808 title "Factors influencing plasma brain natriuretic peptide in patients with restrictive cardiomyopathy" @default.
- W2369791808 hasPublicationYear "2011" @default.
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