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- W2369834902 abstract "OBJECTIVE:To study antibacterial effects of Zhili granule on mice infected with E.coli or dysentery bacilli and its acute toxicity on mice.METHODS:Mice were randomized to normal control group,positive control group and zhili granule groups(2.5g·kg-1,5.0g·kg-1 and 10.0g·kg-1).All mice were injected intraperitoneally with quantitative bacterium solutions 30 minutes prior to being administered intragastrically with corresponding medicines once daily for 7 consecutive days.The number of dead mice in each group was recorded.RESULTS:At a dose of 5.8g·kg-1 zhili granule had good anti-infective effect on mice infected by E.coli and at a dose of 10.0g·kg-1 it had good anti-infective effect on mice infected by dysentery bacterium.Acute toxicity text showed that maximal tolerance of experimental mice to zhili granule was about 104 times as the recommendede dose(15g/bag)in clinic,and oral administration of zhili granule proved to be safe.CONCLUSION:Zhili granule had obvious antibacterial action and it was safe to use orally." @default.
- W2369834902 created "2016-06-24" @default.
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- W2369834902 date "2007-01-01" @default.
- W2369834902 modified "2023-09-23" @default.
- W2369834902 title "Antibacterial Action and Acute Toxicity Tests of Zhili Granule" @default.
- W2369834902 hasPublicationYear "2007" @default.
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