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- W2369851990 abstract "Phylogenetic profiling is the mostly researched non-homology based functional annotation method.This paper introduced the basic theory of phylogenetic profiling method,and improved this method in two aspects: one is to construct weight based phylogenetic profile;the other is to use refined clustering arithmetic for the analysis of similarity among profiles.We downloaded 100 Escherichia coli K12 proteins from NCBI as experimentation data,and use hierarchical cluster method,K-means algorithm and our method to analyze the profiles respectively.The results indicated that our method showed a higher accuracy compared with the former two methods in clustering of similar profiles." @default.
- W2369851990 created "2016-06-24" @default.
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- W2369851990 date "2009-01-01" @default.
- W2369851990 modified "2023-09-23" @default.
- W2369851990 title "Application of Improved Phylogenetic Profiling Method in Protein Functional Annotation" @default.
- W2369851990 hasPublicationYear "2009" @default.
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