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- W2369857597 abstract "Objective To investigate the expressions and their significances of extracellular matrix metalloproteinase inducer(CD147) mRNA and laminin receptor(LN-R) mRNA in human gliomas.Methods Reverse transcriptase-polymerase chain reaction(RT-PCR) was applied to analyze the expression levels of CD147 mRNA and LN-R mRNA in human glioma tissues in 48 patients.Results The positivity rates of CD147 and LN-R in human gliomas were 66.67% and 58.33% respectively,and the co-expression rate of CD147 and LN-R was 56.25%.The expression of CD147 mRNA was positively correlated with LN-R mRNA(r=0.815,P0.01).The expression levels of CD147 mRNA and LN-R mRNA were increased with the increase of glioma grade and invasion ability.Conclusion The expression levels of CD147 and LN-R are closely related with the malignant degree of gliomas,and could be used as reference indexes for prognosis and therapeutic efficacy of human gliomas." @default.
- W2369857597 created "2016-06-24" @default.
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- W2369857597 date "2009-01-01" @default.
- W2369857597 modified "2023-09-23" @default.
- W2369857597 title "Expressions and their significance of extracellular matrix metalloproteinase inducer mRNA and laminin receptor mRNA in human gliomas" @default.
- W2369857597 hasPublicationYear "2009" @default.
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