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- W2369878436 abstract "Objective To evaluate the diagnostic value of brain natriuretic peptide (BNP) for cardiac dyspnea.Methods Plasma BNP levels were measured by radioimmunoassay in dyspnea patients with chronic heart failure (CHF) (n=52) or without CHF (n=30) and normal control group (n=28).Results The BNP level in dyspnea patients with CHF was significantly higher than that of dyspnea patients without CHF and normal control group [(649.80±141.72) pg/mL vs (59.08±18.60) pg/mL and (65.20±16.32) pg/mL,respectively,P0.05].There was no significant difference of BNP level between dyspnea patients without CHF and normal group (P0.05).The plasma BNP level elevated with the worsening of heart failure (NYHA Classiffication).The BNP level in dyspnea patients with CHF was negatively correlated with left ventricle ejection fraction (r=-0.673,P0.001).The receiver operating characteristic (ROC) curve analysis showed that the area under the ROC curve (AUC) is 0.91(0.88-0.98,P0.001) with a sensitivity of 87.2% and a specificity of 86.8% at the cutoff value of 206 pg/mL.Conclusion Measurement of plasma BNP is a rapid diagnostic method for cardiac dyspnea." @default.
- W2369878436 created "2016-06-24" @default.
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- W2369878436 date "2007-01-01" @default.
- W2369878436 modified "2023-09-23" @default.
- W2369878436 title "Diagnostic significance of brain natriuretic peptide in cardiac dyspnea" @default.
- W2369878436 hasPublicationYear "2007" @default.
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