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- W2369903249 abstract "Objective:To study the effect of erigeron breviscapus on TGF-β1 and renal function of diabetes rats. Methods: 70 healthy male rats were selected and divided randomly into one normal group (N) with 20 rats, one diabetes group (DM) with 25 rats and one breviscanine treatment group (EB) with 25 rats. The later two groups were made as a diabetes nephropathy model induced by injecting streptozotocin (STZ). N group and DM group were injected into the abdominal cavity with normal saline solution while EB group was injected the abdominal cavity with 20mg.kg-1d-1 erigeron breviscapus. These rats were killed after a 2-week and a 6-week medicine treatment to collect blood to examine serum TGF-β1, creatinine (Cre) and blood urea nitrogen (Bun). Results: A. The level of the serum TGF-β1, Cre and BUN was the diabetes group the breviscanine treatment groupthe normal group and the decrease of Cre was more obvious in the 2-week group (P0.01); B. The comparison of urea creatinine egestion was the normal group the breviscanine treatment group the diabetes group. The statistical difference was (P0.05). Conclusion: Erigeron breviscapus may inhibit the renal overgrowth, increase the urea creatinine egestion and reduce the concentration of Bun and Cre through the influence of TGF-β1, thus protecting Kidney." @default.
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- W2369903249 date "2008-01-01" @default.
- W2369903249 modified "2023-09-28" @default.
- W2369903249 title "An Experimental Study on the Effect of Erigeron Breviscapus on TGF-β1 and Renal Function of Diabetes Rats" @default.
- W2369903249 hasPublicationYear "2008" @default.
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