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- W2369915227 abstract "Objective To investigate the relationship of VEGF-D(vascular endothelial growth factor D) with lymphangiogenesis and lymph node metastasis of human epithelial ovarian carcinoma.Methods The expression of VEGF-D protein was examined in 78 cases of ovarian carcinoma by immunohistochemistry.D2-40 was measured for detecting lymphatic vessels as the specific marker of lymphatic endothelium.Results VEGF-D protein was detected in cytoplasm of malignant cells,expression level of VEGF-D protein in lymph node metastatic ovarian carcinoma was significantly higher than that in nonmetastatic group(P0.01).The lymphatic vessels density(LVD) was also higher in lymph node metastatic group than in nonmetastatic group significantly(P0.01).VEGF-D expression was closely related to the tumor LVD and lymph node metastasis of carcinoma.Conclusion VEGF-D correlates with lymphangiogenesis and lymph node metastasis in ovarian carcinoma." @default.
- W2369915227 created "2016-06-24" @default.
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- W2369915227 date "2009-01-01" @default.
- W2369915227 modified "2023-09-25" @default.
- W2369915227 title "The Relationship between Vascular Endothelial Growth Factor D Expression and Lymph Node Metastasis in Human Epithelial Ovarian Carcinoma" @default.
- W2369915227 hasPublicationYear "2009" @default.
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