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- W2369926714 abstract "Objective To investigate the immunophenotypic characteristics in chronic lymphoblastic leukemia(CLL).Methods Immunophenotyping was performed in 126 patients with CLL by three/four-color multiparameter flow cytometry analysis using a panel of monoclonal antibodies.Results Among the 126 cases of CLL,117 were B lineage-CLL,8 were T lineage-CLL.All of the B-CLL cases expressed CD19,the positive ratio of other B lineage antigen such as CD20,CD22,and CD23 was 88.6%,66%,74.2%,respectively.None of the B-CLL cases expressed FMC7 and CD10.Of the B-CLL cases 79.1% was CD5+ and 20.9% was CD5-.ZAP-70 protein and CD38 were analyzed in 45 patients with CD5+ B-CLL.ZAP-70 and CD38 co-expressed in 14 cases.4 cases were CD38+ZAP-70-.3 cases were CD38-ZAP-70+.24 cases were CD38-ZAP-70-.All of the 9 T-CLL cases with mature T cell immunophenotypic characters only expressed T lineage antigen and none of the B lineage antigen were expressed.Conclusion Immunophenotypic data is very important for the diagnosis and prognosis of CLL,but the relationship between the immunophenotypic character and the prognosis of CLL need further study." @default.
- W2369926714 created "2016-06-24" @default.
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- W2369926714 date "2006-01-01" @default.
- W2369926714 modified "2023-09-22" @default.
- W2369926714 title "An Analysis of Immunophenotyping Characteristics in 126 Cases with Chronic Lymphoblastic Leukemia" @default.
- W2369926714 hasPublicationYear "2006" @default.
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