Matches in SemOpenAlex for { <https://semopenalex.org/work/W2369936089> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2369936089 abstract "Aim To investigate the relationship between tetrandrine(Tet) on prevention and treatment of restenosis and phenotypic modulation of vascular smooth muscle cells(VSMC) as well as its signal transduction pathway after vascular intimal injury. Methods HE staining was used to analyse vascular morphology change at sham-injured,injured and Tet-treated group 28 days.Immunohistochemistry and Western blot were respectively used to detect the expression change of smooth muscle α-actin(SM α-actin) and proliferation cell nuclear antigen(PCNA),p38 in injured group and Tet group at 7,14 and 28 days after balloon injury. Results The every layer structure in vascular wall of sham-injured artery was intact.Neointimal area was obviously increased and lumen area was notably decreased in injured group.In the Tet group the intimal proliferation was showed but notably weaker than that of the injured group and lumen area notably increased.Compared with the injured group,the expression of SM α-actin,PCNA and p38 in vascular wall of the Tet group was not significantly different and neointimal proliferation degree was also basicly the same at 7 days after injury.The expression of PCNA and p38 in Tet group was all significantly lower than that in injured group in vascular wall at 14 and 28 days after injury.However,expression of SM α-actin in Tet group was slightly higher than that in injured group at 14 days, and not significantly different between the two groups at 28 days. Conclusion Tet could reduce neointimal hyperplasia by inhibiting VSMC phenotypic modulation and its signal transduction." @default.
- W2369936089 created "2016-06-24" @default.
- W2369936089 creator A5052957731 @default.
- W2369936089 date "2006-01-01" @default.
- W2369936089 modified "2023-09-25" @default.
- W2369936089 title "Effects of Tetrandrine on Phenotypic Modulation of Vascular Smooth Muscle Cells and Expression of p38 after Intimal Injury" @default.
- W2369936089 hasPublicationYear "2006" @default.
- W2369936089 type Work @default.
- W2369936089 sameAs 2369936089 @default.
- W2369936089 citedByCount "0" @default.
- W2369936089 crossrefType "journal-article" @default.
- W2369936089 hasAuthorship W2369936089A5052957731 @default.
- W2369936089 hasConcept C126322002 @default.
- W2369936089 hasConcept C131631996 @default.
- W2369936089 hasConcept C142724271 @default.
- W2369936089 hasConcept C204232928 @default.
- W2369936089 hasConcept C207865475 @default.
- W2369936089 hasConcept C2776820930 @default.
- W2369936089 hasConcept C2777339539 @default.
- W2369936089 hasConcept C2777562237 @default.
- W2369936089 hasConcept C2778095995 @default.
- W2369936089 hasConcept C2778283817 @default.
- W2369936089 hasConcept C2778583881 @default.
- W2369936089 hasConcept C2779395532 @default.
- W2369936089 hasConcept C2779751240 @default.
- W2369936089 hasConcept C2779934757 @default.
- W2369936089 hasConcept C2780559512 @default.
- W2369936089 hasConcept C2992686903 @default.
- W2369936089 hasConcept C34688535 @default.
- W2369936089 hasConcept C71924100 @default.
- W2369936089 hasConcept C86803240 @default.
- W2369936089 hasConceptScore W2369936089C126322002 @default.
- W2369936089 hasConceptScore W2369936089C131631996 @default.
- W2369936089 hasConceptScore W2369936089C142724271 @default.
- W2369936089 hasConceptScore W2369936089C204232928 @default.
- W2369936089 hasConceptScore W2369936089C207865475 @default.
- W2369936089 hasConceptScore W2369936089C2776820930 @default.
- W2369936089 hasConceptScore W2369936089C2777339539 @default.
- W2369936089 hasConceptScore W2369936089C2777562237 @default.
- W2369936089 hasConceptScore W2369936089C2778095995 @default.
- W2369936089 hasConceptScore W2369936089C2778283817 @default.
- W2369936089 hasConceptScore W2369936089C2778583881 @default.
- W2369936089 hasConceptScore W2369936089C2779395532 @default.
- W2369936089 hasConceptScore W2369936089C2779751240 @default.
- W2369936089 hasConceptScore W2369936089C2779934757 @default.
- W2369936089 hasConceptScore W2369936089C2780559512 @default.
- W2369936089 hasConceptScore W2369936089C2992686903 @default.
- W2369936089 hasConceptScore W2369936089C34688535 @default.
- W2369936089 hasConceptScore W2369936089C71924100 @default.
- W2369936089 hasConceptScore W2369936089C86803240 @default.
- W2369936089 hasLocation W23699360891 @default.
- W2369936089 hasOpenAccess W2369936089 @default.
- W2369936089 hasPrimaryLocation W23699360891 @default.
- W2369936089 hasRelatedWork W1964234749 @default.
- W2369936089 hasRelatedWork W1968142145 @default.
- W2369936089 hasRelatedWork W2106390653 @default.
- W2369936089 hasRelatedWork W2349414643 @default.
- W2369936089 hasRelatedWork W2358130632 @default.
- W2369936089 hasRelatedWork W2363013720 @default.
- W2369936089 hasRelatedWork W2367988640 @default.
- W2369936089 hasRelatedWork W2371196160 @default.
- W2369936089 hasRelatedWork W2373599627 @default.
- W2369936089 hasRelatedWork W2375216120 @default.
- W2369936089 hasRelatedWork W2377697453 @default.
- W2369936089 hasRelatedWork W2378382191 @default.
- W2369936089 hasRelatedWork W2385084833 @default.
- W2369936089 hasRelatedWork W2385445882 @default.
- W2369936089 hasRelatedWork W2385617390 @default.
- W2369936089 hasRelatedWork W2386919489 @default.
- W2369936089 hasRelatedWork W2387649992 @default.
- W2369936089 hasRelatedWork W2390947625 @default.
- W2369936089 hasRelatedWork W2410965209 @default.
- W2369936089 hasRelatedWork W3147237859 @default.
- W2369936089 isParatext "false" @default.
- W2369936089 isRetracted "false" @default.
- W2369936089 magId "2369936089" @default.
- W2369936089 workType "article" @default.