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- W2369948730 abstract "Objective To explore the relationship between Parkinson disease (PD)sensitivity and the 40-bp variable number of tandem repeats (VNTR) polymorphism of dopamine transporter (DAT) gene in a Chinese Han population of Shanghai area. Methods Molecular analysis of the VNTR polymorphism of DAT gene was performed with amplified fragment length polymorphism (Amp-FLP). Association analysis was carried out in 144 unrelated idiopathic PD patients and 184 age-matched healthy controls. Results In our samples,10 repeats (480 bp) variant was the dominant allele of DAT VNTR polymorphisms with the allelic frequency 0.93 in PD and 0.90 in control. No significant association was found between this VNTR polymorphism and PD ( P 0.05). Conclusions Our results do not support that DAT VNTR polymorphism is associated with PD in Chinese Han population of Shanghai area." @default.
- W2369948730 created "2016-06-24" @default.
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- W2369948730 date "2004-01-01" @default.
- W2369948730 modified "2023-09-28" @default.
- W2369948730 title "Parkinson's disease sensitivity and the 40-bp VNTR polymorphism of DAT gene" @default.
- W2369948730 hasPublicationYear "2004" @default.
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