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- W2369949304 abstract "Objective To analyse the clinical feature and therapeutic effect of glucocorticoid and intensive insulintherapyonprognosisindiabetic patients with severe acute respiratory syndrome (SARS). Methods Eighty-nine patients with a clinical diagnosis of SARS were observed between March and May 2003, including 15 diabetic cases (diabetes SARS group) and 74 non-diabetic cases (non-diabetes SARS group). All patients were treated essentially with the same scheme. Diabetes SARS group was treated by glucocorticoids and intensive insulin therapy. Pulmonary lesion, leucocyte count, T lymphocyte subgroup, lactate dehydrogenase (LDH) etc. were observed in both groups. Results By X-ray examination, 43 lobes of lungs were infected in 15 diabetic patients with SARS (average 2.9 lobes per case) and 108 lobes in 69 non-diabetic patients with SARS (average 1.6 lobes per case), but there was no statistical significance between 2 groups. LDH level can reflect the extent of pulmonary lesions and there was a significant difference between diabetes SARS group (337±186)IU/L and non-diabetic SARS group (187±136)IU/L (P0.05). During glucocorticoid therapy, the diabetics showed marked disturbance of glucose metabolism and were susceptible to the secondary infection by bacteria, so that these patients had to be treated by intensive insulin therapy for blood glucose control. Conclusion Diabetes is a susceptible factor to the infection of SARS. As compared with non-diabetes SARS group, diabetes SARS patients were older and had more severe manifestations, more chances to secondary bacterial infections and prolonged hospitalization. It is necessary to control hyperglycemia and to apply appropriate dose of glucocorticoid in diabetic SARS patients." @default.
- W2369949304 created "2016-06-24" @default.
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- W2369949304 date "2004-01-01" @default.
- W2369949304 modified "2023-09-26" @default.
- W2369949304 title "Clinical feature and therapeutic experience in diabetic patients with severe acute respiratory syndrome" @default.
- W2369949304 hasPublicationYear "2004" @default.
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