Matches in SemOpenAlex for { <https://semopenalex.org/work/W2369969211> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2369969211 abstract "Aim To study the effects of 2-propylpentanoic acid(VPA) on proliferation and apoptosis in human glioblastoma cell lines in vitro in order to provide a theoretical basis for clinical treatment.Methods 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay was used to determine the cell proliferation.The effects on cell cycle arrest and cell apoptosis were observed by flow cytometry,and the expression of acetyl-histone H3 and H4 were detected by Western blot.Results VPA inhibited cell proliferation in the glioblastoma cell lines SF295 and U87;G2/M phase arrest was induced by VPA.The expression of aceyl-histone H3 and H4 was significantly increased in a time-dependence manner.Apoptosis emerged after a high concentration treatment with VPA.Conclusion VPA may inhibit the proliferation of glioblastoma cell lines,induce cell cycle arrest,and promote apoptosis,which could result from ptomoting histone acetylation." @default.
- W2369969211 created "2016-06-24" @default.
- W2369969211 creator A5057239115 @default.
- W2369969211 date "2013-01-01" @default.
- W2369969211 modified "2023-09-23" @default.
- W2369969211 title "Effects of 2-propylpentanoic acid on proliferation and apoptosis in human glioblastoma cell lines" @default.
- W2369969211 hasPublicationYear "2013" @default.
- W2369969211 type Work @default.
- W2369969211 sameAs 2369969211 @default.
- W2369969211 citedByCount "0" @default.
- W2369969211 crossrefType "journal-article" @default.
- W2369969211 hasAuthorship W2369969211A5057239115 @default.
- W2369969211 hasConcept C104317684 @default.
- W2369969211 hasConcept C105696609 @default.
- W2369969211 hasConcept C119157956 @default.
- W2369969211 hasConcept C1491633281 @default.
- W2369969211 hasConcept C153911025 @default.
- W2369969211 hasConcept C185592680 @default.
- W2369969211 hasConcept C190283241 @default.
- W2369969211 hasConcept C2780783641 @default.
- W2369969211 hasConcept C29537977 @default.
- W2369969211 hasConcept C502942594 @default.
- W2369969211 hasConcept C54355233 @default.
- W2369969211 hasConcept C553184892 @default.
- W2369969211 hasConcept C55493867 @default.
- W2369969211 hasConcept C62112901 @default.
- W2369969211 hasConcept C81885089 @default.
- W2369969211 hasConcept C86803240 @default.
- W2369969211 hasConcept C95444343 @default.
- W2369969211 hasConceptScore W2369969211C104317684 @default.
- W2369969211 hasConceptScore W2369969211C105696609 @default.
- W2369969211 hasConceptScore W2369969211C119157956 @default.
- W2369969211 hasConceptScore W2369969211C1491633281 @default.
- W2369969211 hasConceptScore W2369969211C153911025 @default.
- W2369969211 hasConceptScore W2369969211C185592680 @default.
- W2369969211 hasConceptScore W2369969211C190283241 @default.
- W2369969211 hasConceptScore W2369969211C2780783641 @default.
- W2369969211 hasConceptScore W2369969211C29537977 @default.
- W2369969211 hasConceptScore W2369969211C502942594 @default.
- W2369969211 hasConceptScore W2369969211C54355233 @default.
- W2369969211 hasConceptScore W2369969211C553184892 @default.
- W2369969211 hasConceptScore W2369969211C55493867 @default.
- W2369969211 hasConceptScore W2369969211C62112901 @default.
- W2369969211 hasConceptScore W2369969211C81885089 @default.
- W2369969211 hasConceptScore W2369969211C86803240 @default.
- W2369969211 hasConceptScore W2369969211C95444343 @default.
- W2369969211 hasOpenAccess W2369969211 @default.
- W2369969211 hasRelatedWork W1570247425 @default.
- W2369969211 hasRelatedWork W2020512478 @default.
- W2369969211 hasRelatedWork W2021379061 @default.
- W2369969211 hasRelatedWork W2064795412 @default.
- W2369969211 hasRelatedWork W2216447807 @default.
- W2369969211 hasRelatedWork W2263513337 @default.
- W2369969211 hasRelatedWork W2373265197 @default.
- W2369969211 hasRelatedWork W2381714013 @default.
- W2369969211 hasRelatedWork W2387465123 @default.
- W2369969211 hasRelatedWork W2410234508 @default.
- W2369969211 hasRelatedWork W2773580833 @default.
- W2369969211 hasRelatedWork W2778503620 @default.
- W2369969211 hasRelatedWork W2788124846 @default.
- W2369969211 hasRelatedWork W2887886797 @default.
- W2369969211 hasRelatedWork W2891937576 @default.
- W2369969211 hasRelatedWork W2992277868 @default.
- W2369969211 hasRelatedWork W3032620667 @default.
- W2369969211 hasRelatedWork W3045408129 @default.
- W2369969211 hasRelatedWork W3164274677 @default.
- W2369969211 hasRelatedWork W3191980758 @default.
- W2369969211 isParatext "false" @default.
- W2369969211 isRetracted "false" @default.
- W2369969211 magId "2369969211" @default.
- W2369969211 workType "article" @default.