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- W2369970926 abstract "The present study aims to analyze the correspondence between intracellular gluthathione (GSH) content and tumour cells sensitivity to γ-rays, to investigate the influence of irradiation on GSH synthesis and to evaluate the feasibility of monitoring patients radiosensitivity by determining GSH in peripheral monocyto. In this experiments, buthionine sulfoximine (BSO), a GSH synthase inhibitor used to adjust intracellular GSH content, was observed its radiosensitization effect in vivo and in vitro. The results indicated that irradiation increased GSH synthese, BSO enhanced cells sensitivity to γ-ray by exhausting intracellulsr GSH, GSH in PMN could be an useful biochemical parameter to monitor patients sensitivity to irradiation." @default.
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- W2369970926 date "2004-01-01" @default.
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- W2369970926 title "A Research on the correspondence between GSH content and cancer radiosensitivity" @default.
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