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- W2369983751 abstract "Objective To investigate the expression of KAI1/CD82 and MMP-9 in gastric carcinoma,and its significance in the prognosis of gastric carcinoma.Methods Sixty-eight gastric carcinoma tissues were studied for the expression of KAI1/CD82 and MMP-9 by means of immunohistochemical assay. 35 cases were followed-up and the prognosis was analyzed. Results Eighteen of 68 cases gastric carcinoma were positive for KAI1 (26.4%), while 59 of 68 for MMP-9(86.76% ). KAI1/CD82 positive rate in well-differentiated carcinoma was higher than that in the poorly-differentiated,but MMP-9 positive rate was not.KAI1/CD82 positive rate in the cases without lymph node metastasis was higher than that in those with lymph node metastasis.The reverse was MMP-9 positive rate.With tumor invasion promoting, KAI1/CD82 positive rate was higher and MMP-9 positive rate was lower. KAI1/CD82 positive rate was lower with tumor stage increasing and MMP-9 positive rate was not significantly changed.The expression of KAI1/CD82 and MMP-9 was not correlated with the age and sex. The patients with KAI1/CD82 positive had higher survival rate than those with KAI1/CD82 negative, while the patients with MMP-9 positive had lower survival rate than those with MMP-9 negative.Conclusion The expression of KAI1 was related to the invasion,differentiation,staging,lymph node metastasis and prognosis of the tumor, and the expression of MMP-9 was related to invasion,lymph node metastasis and prognosis of the tumor." @default.
- W2369983751 created "2016-06-24" @default.
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- W2369983751 date "2006-01-01" @default.
- W2369983751 modified "2023-09-23" @default.
- W2369983751 title "The expression and clinical significance of KAI1/CD82 and MMP-9 in gastric adenocarcinoma" @default.
- W2369983751 hasPublicationYear "2006" @default.
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