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- W2370009110 abstract "Objective To explore the characteristics of serum lipid and apolipoprotein profile in military pilots,and to better understand the associations between apolipoproteins with lipids. Methods The present study was performed in 180 male military pilots who were recruited randomly. They all underwent a physical examination and their serum apolipoprotein(apo)A1,A2,B,C2,C3, E and lipids were assayed.Results ①Serum apoA2,apoB,apoC3 and apoE increased with age (aged 23～56 years)significantly;②compared with pilots without lipid disorder,apoB(0.920± 0.237 vs 0.789±0.207g/L,t=-2.875,P=0.005),apoC2(0.066±0.016 vs 0.039±0.015g/L, t=-8.151,P=0.000),apoC3(0.169±0.054 vs 0.108±0.028g/L,t=-5.611,P=0.000)and apoE(0.056±0.011 vs 0.043±0.009g/L,t=-6.408,P=0.000)increased,while apoA1(1.309 ±0.143 vs 1.421±0.213g/L,t=2.586,P=0.011)decreased in the hypertriglyceridemias,all apos increased in hypercholesteremias or combined hypertriglyceridemias(P0.01),apoA1(1.096± 0.166 vs 1.421±0.213g/L,t=6.754,P=0.000),apoA2(0.252±0.028 vs 0.292±0.041g/L, t=3.557,P=0.001)decreased and apoC2(0.187±0.069 vs 0.039~±.015g/L,t=-3.513,P= 0.000),apoC3(0.169±0.064 vs 0.108±0.028g/L,t=-4.176,P=0.001),apoE(0.054±0.028 vs 0.043±0.009g/L,t=-3.177,P=0.002)increased in the hypertriglyceridemias combined with hypo-high density lipoprotein-cholesteremias(HDL-C);③total cholesterol(TC)was positively correlated with all apos;triglyceride(TG)was positively correlated with apoB(r=0.349,P0.01), apoC2(r=0.517,P0.01),apoC3(r=0.746,P0.01)and apoE(r=0.621,P0.01),HDL- C was positively correlated with apoA1(r=0.873,P0.01),apoA2(r=0.494,P0.01)and negatively correlated with apoC2(r=-0.152,P0.05);low density lipoprotein-cholesteremias (LDL-C)was positively correlated with apoA2(r=0.295,P0.01),apoB(r=0.864,P0.01) and apoE(r=0.273,P0.01).Conclusions Among 180 male military pilots,serum apoA2, apoB,apoC3 and apoE were related to age,all apolipoproteins were closely associated with lipid disorders." @default.
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- W2370009110 date "2007-06-15" @default.
- W2370009110 modified "2023-09-23" @default.
- W2370009110 title "Study of serum apolipoprotein profile and its association with serum lipid among military pilots" @default.
- W2370009110 doi "https://doi.org/10.3760/cma.j.issn.1007-6239.2007.02.007" @default.
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