Matches in SemOpenAlex for { <https://semopenalex.org/work/W2370030428> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2370030428 abstract "Objective To study the safety and neuroprotection of selective brain hypothermia in term neonates with hypoxic ischemic brain damage after birth asphyxia. With the parental approval, eighteen newborns (gestation ≥37 weeks, Apgar score ≤5 after 5 min) with clinical evidence of encephalopathy and abnormal EEG were enrolled in the first 6 h after birth. Methods Infants were divided randomly into the control group[rectal temperature(36.5±0.5)℃, n =7]and the treatment group[rectal temperature (34.5±0.3)℃, nasopharyngeal temperature (34.0±0.2)℃, n =11]. The head hypothermia in the treatment group was induced by circulating water cooling cap for up to 72 h. Blood samples were taken 72 hours after birth and analyzed for D dimer,troponin T and β 2 microglobulin (β 2 MG). The cerebrospinal fluid samples were detected for neuron specific enolase (NSE). A 16 channel EEG was recorded 4 6 hours, 7 10 days and 3 months after birth. Neurodevelopmental assessment was evaluated with neonatal behavioral neurological assessment (NBNA) 1, 3 and 6 months after birth. Results A significant elevation in plasma D dimer,troponin T and β 2 MG was observed in both groups ( P 0 05), but NSE in the control group was higher than in the treatment group [(24.6±5.3) μg/L vs (18.1±2.1) μg/L, t =2.04, P 0.01].In the treatment group NBNA was improved 28 days after birth compared to the control group ( t =1.83, P 0.01).EEG was normal in the treatment group 7 days after birth. Conclusions The neuroprotection of selective hypothermia could be tracked by the neurodevelopmental, biochemical, and EEG measures. The adverse effect on cardiac, kidney and coagulation function were slight in term newborns." @default.
- W2370030428 created "2016-06-24" @default.
- W2370030428 creator A5045634296 @default.
- W2370030428 date "2001-01-01" @default.
- W2370030428 modified "2023-09-25" @default.
- W2370030428 title "Neuroprotection of selective brain hypothermia to neonates with the hypoxic-ischemic brain damage" @default.
- W2370030428 hasPublicationYear "2001" @default.
- W2370030428 type Work @default.
- W2370030428 sameAs 2370030428 @default.
- W2370030428 citedByCount "0" @default.
- W2370030428 crossrefType "journal-article" @default.
- W2370030428 hasAuthorship W2370030428A5045634296 @default.
- W2370030428 hasConcept C126322002 @default.
- W2370030428 hasConcept C188618488 @default.
- W2370030428 hasConcept C204232928 @default.
- W2370030428 hasConcept C25498285 @default.
- W2370030428 hasConcept C2777390192 @default.
- W2370030428 hasConcept C2778052368 @default.
- W2370030428 hasConcept C2778376644 @default.
- W2370030428 hasConcept C2778621155 @default.
- W2370030428 hasConcept C2779234561 @default.
- W2370030428 hasConcept C2779914510 @default.
- W2370030428 hasConcept C2780164069 @default.
- W2370030428 hasConcept C2781458332 @default.
- W2370030428 hasConcept C2909832856 @default.
- W2370030428 hasConcept C42219234 @default.
- W2370030428 hasConcept C54355233 @default.
- W2370030428 hasConcept C71924100 @default.
- W2370030428 hasConcept C86803240 @default.
- W2370030428 hasConceptScore W2370030428C126322002 @default.
- W2370030428 hasConceptScore W2370030428C188618488 @default.
- W2370030428 hasConceptScore W2370030428C204232928 @default.
- W2370030428 hasConceptScore W2370030428C25498285 @default.
- W2370030428 hasConceptScore W2370030428C2777390192 @default.
- W2370030428 hasConceptScore W2370030428C2778052368 @default.
- W2370030428 hasConceptScore W2370030428C2778376644 @default.
- W2370030428 hasConceptScore W2370030428C2778621155 @default.
- W2370030428 hasConceptScore W2370030428C2779234561 @default.
- W2370030428 hasConceptScore W2370030428C2779914510 @default.
- W2370030428 hasConceptScore W2370030428C2780164069 @default.
- W2370030428 hasConceptScore W2370030428C2781458332 @default.
- W2370030428 hasConceptScore W2370030428C2909832856 @default.
- W2370030428 hasConceptScore W2370030428C42219234 @default.
- W2370030428 hasConceptScore W2370030428C54355233 @default.
- W2370030428 hasConceptScore W2370030428C71924100 @default.
- W2370030428 hasConceptScore W2370030428C86803240 @default.
- W2370030428 hasLocation W23700304281 @default.
- W2370030428 hasOpenAccess W2370030428 @default.
- W2370030428 hasPrimaryLocation W23700304281 @default.
- W2370030428 hasRelatedWork W2068084551 @default.
- W2370030428 hasRelatedWork W2083931913 @default.
- W2370030428 hasRelatedWork W2182808649 @default.
- W2370030428 hasRelatedWork W2287395491 @default.
- W2370030428 hasRelatedWork W2318780359 @default.
- W2370030428 hasRelatedWork W2324200918 @default.
- W2370030428 hasRelatedWork W2379082129 @default.
- W2370030428 hasRelatedWork W2587779443 @default.
- W2370030428 hasRelatedWork W2765279323 @default.
- W2370030428 hasRelatedWork W2792373560 @default.
- W2370030428 hasRelatedWork W2922506467 @default.
- W2370030428 hasRelatedWork W3026506935 @default.
- W2370030428 hasRelatedWork W3028636199 @default.
- W2370030428 hasRelatedWork W3028650866 @default.
- W2370030428 hasRelatedWork W3029998342 @default.
- W2370030428 hasRelatedWork W3030041239 @default.
- W2370030428 hasRelatedWork W3031348814 @default.
- W2370030428 hasRelatedWork W3031593563 @default.
- W2370030428 hasRelatedWork W3031843109 @default.
- W2370030428 hasRelatedWork W3032644274 @default.
- W2370030428 isParatext "false" @default.
- W2370030428 isRetracted "false" @default.
- W2370030428 magId "2370030428" @default.
- W2370030428 workType "article" @default.