FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2370051142> ?p ?o ?g. }

• W2370051142 endingPage "164" @default.
• W2370051142 startingPage "151" @default.
• W2370051142 abstract "As serotoninergic transmission plays a crucial role in higher brain function in mammals, the disturbance of this system will likely have significant effects on emotion and cognition. Previous studies have reported that chronic treatment with Specific Serotonin Reuptake Inhibitors (SSRIs) during both late pregnancy and lactation was associated with abnormal behavior in adult rats. These data imply that disturbances in serotoninergic transmission during neurodevelopment may have negative effects on both the structure and function of the resultant adult brain. Therefore, the effect of a single exposure to an SSRI or a tricyclic antidepressant that preferentially inhibits serotonin reuptake during the pre-weaning period was examined in adult mice. An oral infusion of paroxetine (70 mg/kg), fluvoxamine (250 mg/kg), clomipramine (180 mg/kg), or saline was administered on postnatal day 14. Starting at 11 weeks of age, mice were assessed using a comprehensive behavioral test battery. Mice treated with paroxetine demonstrated altered behavior on the open field and hole-board tasks; those treated with fluvoxamine had behavioral changes on the light-dark box, hole-board, and sucrose preference tasks, while alteration in forced swimming and cued fear behavior were noted in mice treated with clomipramine. These results suggest that even a single administration of an antidepressant could have profound effects on behavior in adulthood, although the effects might differ dependent on the specific drug that was administered." @default.
• W2370051142 created "2016-06-24" @default.
• W2370051142 creator A5025756755 @default.
• W2370051142 date "2016-01-01" @default.
• W2370051142 modified "2023-10-16" @default.
• W2370051142 title "Single Exposure to Antidepressants during Infancy Is Associated with Delayed Behavioral Changes in C57BL/6 Mice" @default.
• W2370051142 cites W1490760214 @default.
• W2370051142 cites W1636271793 @default.
• W2370051142 cites W1733039147 @default.
• W2370051142 cites W1747592977 @default.
• W2370051142 cites W1963956528 @default.
• W2370051142 cites W1971993301 @default.
• W2370051142 cites W1979361034 @default.
• W2370051142 cites W1983205164 @default.
• W2370051142 cites W1985190460 @default.
• W2370051142 cites W1991155688 @default.
• W2370051142 cites W1992991045 @default.
• W2370051142 cites W1996401879 @default.
• W2370051142 cites W2004772207 @default.
• W2370051142 cites W2010804806 @default.
• W2370051142 cites W2019300513 @default.
• W2370051142 cites W2023682546 @default.
• W2370051142 cites W2026460774 @default.
• W2370051142 cites W2029344627 @default.
• W2370051142 cites W2031409382 @default.
• W2370051142 cites W2031747285 @default.
• W2370051142 cites W2031897279 @default.
• W2370051142 cites W2034396455 @default.
• W2370051142 cites W2042900031 @default.
• W2370051142 cites W2044271414 @default.
• W2370051142 cites W2044561516 @default.
• W2370051142 cites W2055716589 @default.
• W2370051142 cites W2057121235 @default.
• W2370051142 cites W2059819000 @default.
• W2370051142 cites W2075975673 @default.
• W2370051142 cites W2079000254 @default.
• W2370051142 cites W2083780981 @default.
• W2370051142 cites W2089776876 @default.
• W2370051142 cites W2093210514 @default.
• W2370051142 cites W2093977667 @default.
• W2370051142 cites W2097007381 @default.
• W2370051142 cites W2108099600 @default.
• W2370051142 cites W2114275748 @default.
• W2370051142 cites W2117155939 @default.
• W2370051142 cites W2124474021 @default.
• W2370051142 cites W2129381979 @default.
• W2370051142 cites W2130162814 @default.
• W2370051142 cites W2141900412 @default.
• W2370051142 cites W2145018075 @default.
• W2370051142 cites W2153038360 @default.
• W2370051142 cites W2158451437 @default.
• W2370051142 cites W2164697276 @default.
• W2370051142 cites W2405662134 @default.
• W2370051142 cites W2412049582 @default.
• W2370051142 cites W824908127 @default.
• W2370051142 doi "https://doi.org/10.4236/wjns.2016.62019" @default.
• W2370051142 hasPublicationYear "2016" @default.
• W2370051142 type Work @default.
• W2370051142 sameAs 2370051142 @default.
• W2370051142 citedByCount "1" @default.
• W2370051142 countsByYear W23700511422020 @default.
• W2370051142 crossrefType "journal-article" @default.
• W2370051142 hasAuthorship W2370051142A5025756755 @default.
• W2370051142 hasBestOaLocation W23700511421 @default.
• W2370051142 hasConcept C118552586 @default.
• W2370051142 hasConcept C126322002 @default.
• W2370051142 hasConcept C134018914 @default.
• W2370051142 hasConcept C136569192 @default.
• W2370051142 hasConcept C15744967 @default.
• W2370051142 hasConcept C169760540 @default.
• W2370051142 hasConcept C170493617 @default.
• W2370051142 hasConcept C173586616 @default.
• W2370051142 hasConcept C2775864247 @default.
• W2370051142 hasConcept C2776134451 @default.
• W2370051142 hasConcept C2777828372 @default.
• W2370051142 hasConcept C2779085643 @default.
• W2370051142 hasConcept C2779177272 @default.
• W2370051142 hasConcept C2779305415 @default.
• W2370051142 hasConcept C2779910183 @default.
• W2370051142 hasConcept C2780092697 @default.
• W2370051142 hasConcept C2781161787 @default.
• W2370051142 hasConcept C31487548 @default.
• W2370051142 hasConcept C37000724 @default.
• W2370051142 hasConcept C558461103 @default.
• W2370051142 hasConcept C71924100 @default.
• W2370051142 hasConceptScore W2370051142C118552586 @default.
• W2370051142 hasConceptScore W2370051142C126322002 @default.
• W2370051142 hasConceptScore W2370051142C134018914 @default.
• W2370051142 hasConceptScore W2370051142C136569192 @default.
• W2370051142 hasConceptScore W2370051142C15744967 @default.
• W2370051142 hasConceptScore W2370051142C169760540 @default.
• W2370051142 hasConceptScore W2370051142C170493617 @default.
• W2370051142 hasConceptScore W2370051142C173586616 @default.
• W2370051142 hasConceptScore W2370051142C2775864247 @default.
• W2370051142 hasConceptScore W2370051142C2776134451 @default.
• W2370051142 hasConceptScore W2370051142C2777828372 @default.
• W2370051142 hasConceptScore W2370051142C2779085643 @default.
• W2370051142 hasConceptScore W2370051142C2779177272 @default.

• next