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- W2370057344 abstract "Objective:To investigate anti-tumor effect and toxicity of tumor-targeting Salmonella typhimurium VNP20009combined with cyclophosphamide(CTX)on the growth of the implanted tongue SCC(squamous cell carcinoma)tumors in nude mouse.Methods:After the establishment of the model,mice were divided into 4groups and the drug was given.Tumor volume was measured and the tumor inhibition rate was calculated.Serum VEGF,ALT,AST and bacteria titer in tumors and livers were examined.Results:Compared with the salmonella or CTX treatment alone,the growth of tumors were significantly inhibited by VNP20009combined with CTX(P0.01).Conclusion:VNP20009combined with CTX has synergistic effect on anti-tumor activity against the growing of tongue SCC tumors." @default.
- W2370057344 created "2016-06-24" @default.
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- W2370057344 date "2010-01-01" @default.
- W2370057344 modified "2023-09-26" @default.
- W2370057344 title "Effects of Tumor-targeting Salmonella Typhimurium VNP20009 Combined with Cyclophosphamide on the Growth of Xenografted Tca8113 Tumors in Nude Mouse" @default.
- W2370057344 hasPublicationYear "2010" @default.
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