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- W2370133418 abstract "Objective: To study genetic bases of graves disease.Methods: Use to observation of sister chromatid exchange;heritability rate analysis and the spontaneous micronucleus rate detection of the lymphocyte cell in Graves patient's peripheral blood.Results: Only mean spontaneous SCE frequency but MMC induced SCE frequency,there are very significantly difference(P0.01)in the hyperthroidiom group and control group.Other,there are significantly difference(P0.01)of the increment of the MMC induced SCE frequency in above two groups;Morbility rate of the first relatives of patient group is 22.3 time than the control group,by χ~2 test,P0.01;there are 34 cases to have obvious family history in the 204 cases of proband of graves disease,to take 16.7% in the proband total,expressing hyperthyroidism to posses tendency of family history;the heritability of graves is 68.6±3.8% in the shantou region;the micronucleus rate of 20 cases patients group and 20 cases control group is respectively 2.55±0.36 and 0.95±0.76,there are significantly difference(P0.01)." @default.
- W2370133418 created "2016-06-24" @default.
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- W2370133418 date "2006-01-01" @default.
- W2370133418 modified "2023-09-26" @default.
- W2370133418 title "Genetics research of Graves disease." @default.
- W2370133418 hasPublicationYear "2006" @default.
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